Desmethyl Erlotinib

CAS No. 183321-86-0

Desmethyl Erlotinib ( CP-473420, OSI-774 )

Catalog No. M12830 CAS No. 183321-86-0

OSI-420 is the active metabolite of Erlotinib (EGFR inhibitor with IC50 of 2 nM).

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 63 Get Quote
5MG 105 Get Quote
10MG 178 Get Quote
25MG 314 Get Quote
50MG 471 Get Quote
100MG 681 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Desmethyl Erlotinib
  • Note
    Research use only, not for human use.
  • Brief Description
    OSI-420 is the active metabolite of Erlotinib (EGFR inhibitor with IC50 of 2 nM).
  • Description
    OSI-420 is the active metabolite of Erlotinib (EGFR inhibitor with IC50 of 2 nM).
  • Synonyms
    CP-473420, OSI-774
  • Pathway
    Angiogenesis
  • Target
    EGFR
  • Recptor
    EGFR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    183321-86-0
  • Formula Weight
    379.41
  • Molecular Formula
    C21H21N3O4
  • Purity
    >98%(HPLC)
  • Solubility
    DMSO:83 mg/mL warmed (199.58 mM);Ethanol:<1 mg/mL;Water:<1 mg/Ml
  • SMILES
    COCCOC1=C(C=C2C(=C1)N=CN=C2NC3=CC=CC(=C3)C#C)OCCO
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Moyer JD, et al. Cancer Res. 1997, 57(21), 4838-4848.
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